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Article

Interaction of beta-catenin and TIF2/GRIP1 in transcriptional activation by the androgen receptor.

The Journal of biological chemistry - 11 Nov 2005

Song Liang-Nian, Gelmann Edward P

Abstract excerpt

The multifunctional oncoprotein beta-catenin interacts with the activation function-2 domain of androgen receptor (AR) to stimulate androgen receptor transcriptional activity, increase sensitivity, and broaden specificity of ligand interactions. beta-Catenin interacts with androgen receptor in close proximity to the binding groove for P160 coactivators such as transcriptional intermediary factor-2...

Read the complete abstract on PubMed

Topics

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Share to Immunoprecipitation
Share to beta Catenin
Share to Protein Structure, Tertiary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Androgen

Share to TCF Transcription Factors

Share to Transcription Factor 7-Like 2 Protein

Share to Transcription, Genetic

Share to Transcriptional Activation

Source

Identifiers

PMID: 16141201
DOI: 10.1074/jbc.M503850200

Genes

GRIP1
TCF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction of beta-catenin and TIF2/GRIP1 in transcriptional activation by the androgen receptor.PMID 16141201Read ↗

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