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Article

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

6 Aug 1996

Abstract excerpt

Transcriptional regulation by nuclear hormone receptors is thought to involve interactions with putative cofactors that may potentiate receptor function. Here we show that human thyroid hormone receptor alpha purified from HeLa cells grown in the presence of thyroid hormone (T3) is associated with a group of distinct nuclear proteins termed thyroid hormone receptor-associated proteins (TRAPs). In an in vitro...

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Identifiers

PMID: 8710870
DOI: 10.1073/pnas.93.16.8329

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