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Article

Reliable detection of p53 aberrations in squamous cell carcinomas of the head and neck requires transcript analysis of the entire coding region.

Head & neck - 1 Sept 2002

Hauser Ulrich, Balz Vera, Carey Thomas E, Grénman Reidar, Van Lierop Anke, Scheckenbach Kathrin, Bier Henning

Abstract excerpt

BACKGROUND: Aberrations of the p53 tumor suppressor gene are common events in squamous cell carcinomas of the head and neck (SCCHN). However, reported frequencies range considerably, and the predictive value of aberrant p53 is continuing to be an issue of controversy. These inconsistencies are possibly caused by methodical limitations. METHODS: In cell lines established from 23 SCCHN, we performed sequence...

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Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

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Source

Identifiers

PMID: 12211051
DOI: 10.1002/hed.10128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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