Article
Molecular assessment of p53 abnormalities at the invasive front of oral squamous cell carcinomas.
Head & neck - 1 Jan 1998
Piffkò J, Bànkfalvi A, Tory K, Füzesi L, Bryne M, Ofner D, Kusch F, Joos U, Schmid K W
Abstract excerpt
BACKGROUND: The prognostic significance of the invasive tumor front in squamous cell carcinomas has recently been recognized. The aim of the present study was to investigate possible molecular mechanisms underlying the significance of this area in oral squamous cell carcinomas. METHODS: We used i...
Topics
- Adult
- Aged
- Biopsy, Needle
- Carcinoma, Squamous Cell
- Chi-Square Distribution
- Disease-Free Survival
- Female
- Gene Expression Regulation, Neoplastic
- Genes, p53
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Mouth Neoplasms
- Mutation
- Neoplasm Invasiveness
- Polymerase Chain Reaction
- Prognosis