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Article

p53 mutation, but not p53 overexpression, correlates with survival in head and neck squamous cell carcinoma.

British journal of cancer - 1 Oct 1998

Mineta H, Borg A, Dictor M, Wahlberg P, Akervall J, Wennerberg J

Abstract excerpt

Survival in squamous cell carcinoma of the head and neck (HNSCC) was compared with overexpression and mutation of the p53 gene. Archival tissue from 77 tumours was analysed for protein expression using immunohistochemistry (IHC) with the monoclonal antibody Do-7, and for the presence of mutation in exons 5-8 using single-stranded conformation polymorphism (SSCP), followed by DNA sequencing in SSCP-positive cases....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, p53

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Share to Polymorphism, Single-Stranded Conformational

Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 9792155
DOI: 10.1038/bjc.1998.632
PMCID: PMC2063151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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