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Article

p53 overexpression in head and neck squamous cell carcinoma: review of the literature.

European journal of cancer. Part B, Oral oncology - 1 May 1996

Raybaud-Diogène H, Tétu B, Morency R, Fortin A, Monteil R A

Abstract excerpt

As a tumour suppressor gene, the inactivation of p53 induces the development of numerous human cancers. Mutations of p53 have been implicated in the pathogenesis of head and neck squamous cell carcinoma (HN-SCC) at a high incidence. In premalignant lesions and in situ carcinomas, p53 overexpression is not exclusively restricted to neoplastic cells, but frequently affects the normal appearing keratinocytes...

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Identifiers

PMID: 8762869
DOI: 10.1016/0964-1955(95)00095-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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