Article
Interaction between the C(-344)T polymorphism of CYP11B2 and age in the regulation of blood pressure and plasma aldosterone levels: cross-sectional and longitudinal findings of the Olivetti Prospective Heart Study.
Journal of hypertension - 1 Sept 2002
Russo Paola, Siani Alfonso, Venezia Antonella, Iacone Roberto, Russo Ornella, Barba Gianvincenzo, D'Elia Lanfranco, Cappuccio Francesco P, Strazzullo Pasquale
Abstract excerpt
OBJECTIVE: To study the interaction between the C(-344)T polymorphism and known determinants (age, body mass and dietary sodium) of blood pressure and plasma aldosterone. DESIGN: Cross-sectional and longitudinal (1980-1995) survey of male workers in southern Italy. SETTING: Medical centre of the Olivetti factories. PARTICIPANTS: In 1995, the C(-344)T polymorphism was characterized in 811 untreated men. A subgroup...
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