Article
-344C/T Variant in the promoter of the aldosterone synthase gene (CYP11B2) is associated with metabolic syndrome in men.
American journal of hypertension - 1 Feb 2007
Russo Paola, Lauria Fabio, Loguercio Maria, Barba Gianvincenzo, Arnout Josef, Cappuccio Francesco P, de Lorgeril Michel, Donati Maria B, Iacoviello Licia, Krogh Vittorio, van Dongen Martien, Siani Alfonso
Abstract excerpt
BACKGROUND: The -344C/T variant in the promoter of the aldosterone synthase gene (CYP11B2) has been associated with hypertension and may influence glucose homeostasis and body mass in humans. We assessed the association between this genetic variant and metabolic syndrome in a large sample of European population. METHODS: Eight hundred two male/female couples, recruited in the framework of the IMMIDIET study, a...
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