Article
Association of the C-344T aldosterone synthase gene variant with essential hypertension: a meta-analysis.
Journal of hypertension - 1 Jan 2007
Sookoian Silvia, Gianotti Tomas Fernández, González Claudio Daniel, Pirola Carlos Jose
Abstract excerpt
BACKGROUND: The CYP11B2 gene (CYP11B2) encoding aldosterone synthase has been associated with essential hypertension and some, but not all, studies have reported that the C-344T variant may influence the risk of the disease. OBJECTIVE: We performed a systematic review of the literature by means of a meta-analysis to evaluate the influence of the C-344T CYP11B2 polymorphism on arterial hypertension and...
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