Article
Aldosterone synthase gene (CYP11B2) C-344T polymorphism, plasma aldosterone, renin activity and blood pressure in a multi-ethnic population.
Journal of hypertension - 1 Oct 2004
Barbato Antonio, Russo Paola, Siani Alfonso, Folkerd Elizabeth J, Miller Michelle A, Venezia Antonella, Grimaldi Claudia, Strazzullo Pasquale, Cappuccio Francesco P
Abstract excerpt
BACKGROUND: The aldosterone synthase gene (CYP1B2) locus is a candidate region involved in the development of hypertension. OBJECTIVE: To study the relationship between the C-344T CYP1B2 polymorphism, plasma aldosterone, renin activity and blood pressure in a multi-ethnic population. DESIGN: Population-based, cross-sectional study of 1313 middle-aged men and women (456 white, 441 of African origin and 416 South...
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