Article
Aldosterone synthase (CYP11B2) C-344T polymorphism affects the association of age-related changes of the serum C-reactive protein.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Apr 2010
Oki Kenji, Yamane Kiminori, Satoh Kenichi, Nakanishi Shuhei, Yamamoto Hideya, Kohno Nobuoki
Abstract excerpt
Aldosterone participates in vascular and myocardial inflammation either directly or indirectly through blood pressure (BP). Aldosterone synthase (CYP11B2) C-344T polymorphism may influence the severity of systemic inflammation. A total of 398 Japanese Americans (152 men and 246 women, age 19-92 years) from the Hawaii-Los Angeles-Hiroshima study were enrolled. BP and serum levels of C-reactive protein (CRP) were...
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