Article

Association of <i>CYP11B2</i> T-344C polymorphism with hypertension and plasma aldosterone in a Ghanaian population

2026-07-14

Abstract excerpt

The Cytochrome P450 Family 11 Subfamily B Member 2 ( CYP11B2 ) is the gene responsible for the synthesis of aldosterone synthase, the enzyme catalysing the terminal steps in the production of aldosterone. Polymorphism at the promoter region of this gene has been implicated to upregulate the synthesis of aldosterone synthase and the downstream production of aldosterone. A high aldosterone (hyperaldosteronism) is a...

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Literature Corpus work: c24dcebe-3ade-5a59-8b0d-c8718a9d2efd
DOI: 10.64898/2026.07.11.26357813

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