Article
C-344T polymorphism of the aldosterone synthase gene and blood pressure in the elderly: a population-based study.
Journal of hypertension - 1 Nov 2005
Casiglia Edoardo, Tikhonoff Valérie, Mazza Alberto, Rynkiewicz Andrzej, Limon Janusz, Caffi Sandro, Guglielmi Francesco, Martini Bortolo, Basso Giancarlo, Winnicki Mikolaj, Pessina Achille C, Somers Virend K
Abstract excerpt
OBJECTIVES: Whether the C-344T polymorphism of the aldosterone synthase gene is important for blood pressure control remains controversial. It has been proposed that an association between this polymorphism and blood pressure might be evident in elderly subjects. The aim of the present study was to test this hypothesis in an epidemiological context. DESIGN: A cross-sectional epidemiological evaluation of a highly...
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