Article

Generalized Structured Component Analysis in candidate gene association studies: applications and limitations

2020-10-08

Abstract excerpt

<h4>Background: </h4> Generalized Structured Component Analysis (GSCA) is a component-based alternative to traditional covariance-based structural equation modelling. This method has previously been applied to test for association between candidate genes and clinical phenotypes, contrasting with traditional genetic association analyses that adopt univariate testing of many individual single nucleotide polymorphism...

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Literature Corpus work: 326f15a9-430e-5f83-a83c-c5c84c841b5f
DOI: 10.12688/wellcomeopenres.15396.2

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