Article
Exploring haplotype sharing methods in general and isolated populations to detect gene(s) of a complex genetic trait.
Genetic epidemiology - 1 Jan 2001
Beckmann L, Fischer C, Deck K G, Nolte I M, te Meerman G, Chang-Claude J
Abstract excerpt
We applied a new haplotype sharing method to the simulated Genetic Analysis Workshop 12 data for both isolated and general populations without knowledge of the disease model, using affection status as phenotype and three different sample sizes. The highest peak for the mean sharing of the haplotypes was found in the isolated population for the markers D06G034 and D06G035, which flank the candidate genes located...
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