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Article

Association testing of clustered rare causal variants in case-control studies.

PloS one - 1 Jan 2014

Lin Wan-Yu

Abstract excerpt

Biological evidence suggests that multiple causal variants in a gene may cluster physically. Variants within the same protein functional domain or gene regulatory element would locate in close proximity on the DNA sequence. However, spatial information of variants is usually not used in current r...

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PMID: 24736372
DOI: 10.1371/journal.pone.0094337
PMCID: PMC3988195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24736372-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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