Article
Influence of antibody diversification on the mechanism of haplotype exclusion of immunoglobulin gene expression.
Seminars in immunology - 1 Jun 2002
Ratcliffe Michael J H, Pike Kelly A
Abstract excerpt
Allelic, or haplotype, exclusion of immunoglobulin gene expression ensures that the products of a single allele or light chain isotype are expressed on the B cell surface. Evidence has accumulated in rodent and primate models to indicate that the products of successful rearrangement regulate this process. In contrast, haplotype exclusion of chicken immunoglobulin gene expression is regulated at the level of...
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