Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of G proteins involved in activation of nonselective cation channels by endothelin(B) receptor.

British journal of pharmacology - 1 Aug 2002

Kawanabe Yoshifumi, Hashimoto Nobuo, Masaki Tomoh

Abstract excerpt

1: We recently demonstrated that endothelin-1 (ET-1) activates two types of Ca(2+)-permeable nonselective cation channels (NSCC-1 and NSCC-2) in Chinese hamster ovary cells expressing endothelin(B) receptors (CHO-ET(B)R) that couple with G(q) and G(i). The purpose of the present study was to identify the G proteins involved in the activation of these Ca(2+) channels by ET-1. For this purpose, we constructed CHO...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium Channels
Share to Endothelin-1
Share to GTP-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microinjections

Share to Receptor, Endothelin B

Share to Receptors, Endothelin

Share to Stress Fibers

Share to Type C Phospholipases

Source

Open in PubMed Open full text

Identifiers

PMID: 12145101
DOI: 10.1038/sj.bjp.0704805
PMCID: PMC1573433

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of G proteins involved in activation of nonselective cation channels by endothelin(B) receptor.PMID 12145101Read ↗

Molecular mechanisms for the activation of voltage-independent Ca2+ channels by endothelin-1 in chinese hamster ovary cells stably expressing human endothelin(A) receptors.Semantic proximity Read ↗

Molecular mechanism for endothelin-1-induced stress-fiber formation: analysis of G proteins using a mutant endothelin(A) receptor.Semantic proximity Read ↗

Molecular mechanisms for activation of voltage-independent Ca2+ channels by endothelin-1/endothelin-A receptors.Semantic proximity Read ↗

Coupling of endothelin receptors to the ERK/MAP kinase pathway. Roles of palmitoylation and G(alpha)q.Semantic proximity Read ↗

Cloning and functional identification of novel endothelin receptor type A isoforms in pituitary.Semantic proximity Read ↗

Modulation of distinct isoforms of L-type calcium channels by G(q)-coupled receptors in Xenopus oocytes: antagonistic effects of Gβγ and protein kinase C.Semantic proximity Read ↗

The first inner loop of endothelin receptor type B is necessary for specific coupling to Galpha 13.Semantic proximity Read ↗

The C-terminus of the prostaglandin-E-receptor EP3 subtype is essential for activation of GTP-binding protein.Semantic proximity Read ↗

Functional domains essential for Gs activity in prostaglandin EP2 and EP3 receptors.Semantic proximity Read ↗

Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel.Semantic proximity Read ↗

Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels.Semantic proximity Read ↗

Mechanisms of endothelin receptor subtype-specific targeting to distinct intracellular trafficking pathways.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.