Article
Molecular mechanisms for the activation of voltage-independent Ca2+ channels by endothelin-1 in chinese hamster ovary cells stably expressing human endothelin(A) receptors.
Molecular pharmacology - 1 Jul 2002
Kawanabe Yoshifumi, Okamoto Yasuo, Miwa Soichi, Hashimoto Nobuo, Masaki Tomoh
Abstract excerpt
We demonstrated recently that in Chinese hamster ovary cells stably expressing human recombinant endothelin(A) receptors (CHO-ET(A)R), endothelin-1 (ET-1) activates two types of Ca2+-permeable nonselective cation channels (designated NSCC-1 and NSCC-2) and a store-operated Ca2+ channel (SOCC), which can be distinguished by Ca(2+) channel blockers such as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.