Article
Mechanisms of endothelin receptor subtype-specific targeting to distinct intracellular trafficking pathways.
The Journal of biological chemistry - 7 Sept 2001
Paasche J D, Attramadal T, Sandberg C, Johansen H K, Attramadal H
Abstract excerpt
We recently reported that the endothelin (ET) receptor subtypes ET(A) and ET(B) are targeted to distinct intracellular destinations upon agonist stimulation (Bremnes, T., Paasche, J. D., Mehlum, A., Sandberg, C., Bremnes, B., and Attramadal, H. (2000) J. Biol. Chem. 275, 17596-17604). The ET(A) receptor was shown to follow the recycling route of transferrin, whereas ET(B) is targeted to lysosomes for degradation....
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