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Article

Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel.

Current biology : CB - 8 Jan 2002

Storey Nina M, O'Bryan John P, Armstrong David L

Abstract excerpt

BACKGROUND: Previous studies of ion channel regulation by G proteins have focused on the larger, heterotrimeric GTPases, which are activated by heptahelical membrane receptors. In contrast, studies of the Rho family of smaller, monomeric, Ras-related GTPases, which are activated by cytoplasmic guanine nucleotide exchange factors, have focused on their role in cytoskeletal regulation. RESULTS: Here we demonstrate...

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Source

Identifiers

PMID: 11790300
DOI: 10.1016/s0960-9822(01)00625-x

Genes

ERG
TRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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