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Article

Modulation of distinct isoforms of L-type calcium channels by G(q)-coupled receptors in Xenopus oocytes: antagonistic effects of Gβγ and protein kinase C.

Channels (Austin, Tex.) - 1 Jan 2000

Weiss Sharon, Keren-Raifman Tal, Oz Shimrit, Ben Mocha Adva, Haase Hannelore, Dascal Nathan

Abstract excerpt

L-type voltage dependent Ca(2+) channels (L-VDCCs; Ca(v)1.2) are crucial in cardiovascular physiology. In heart and smooth muscle, hormones and transmitters operating via G(q) enhance L-VDCC currents via essential protein kinase C (PKC) involvement. Heterologous reconstitution studies in Xenopus...

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Source

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Identifiers

PMID: 22990911
DOI: 10.4161/chan.22016
PMCID: PMC3536727

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22990911-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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