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Article

Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels.

Proceedings of the National Academy of Sciences of the United States of America - 10 Jan 2006

Kawasaki Brian T, Liao Yanhong, Birnbaumer Lutz

Abstract excerpt

Receptor-operated Ca2+ entry (ROCE) and store-operated Ca2+ entry (SOCE) are known to be inhibited by tyrosine kinase inhibitors and activation of C-type transient receptor potential channel (TRPC) isoform 3 (TRPC3), a cation channel thought to be involved in SOCE and/or ROCE, was recently shown to depend on src tyrosine kinase activity. What is not known is the step at which src acts on TRPC3 and whether the...

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Source

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Identifiers

PMID: 16407161
DOI: 10.1073/pnas.0508030102
PMCID: PMC1326167

Genes

TRPC3
TRPC6
TRPC7
TRPC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels.PMID 16407161Read ↗

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Tyrosine 284 phosphorylation is required for ClC-3 chloride channel activation in vascular smooth muscle cells.Semantic proximity Read ↗

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