Article
The C-terminus of the prostaglandin-E-receptor EP3 subtype is essential for activation of GTP-binding protein.
European journal of biochemistry - 15 Aug 1994
Irie A, Sugimoto Y, Namba T, Asano T, Ichikawa A, Negishi M
Abstract excerpt
Three isoforms of the mouse prostaglandin-E-receptor EP3 subtype (EP3), EP3 alpha, EP3 beta and EP3 gamma, with different C-termini, which are produced through alternative splicing, showed different efficiencies with respect to heterotrimeric GTP-binding protein activation and adenylate cyclase i...
Topics
- Adenylyl Cyclase Inhibitors
- Amino Acid Sequence
- Animals
- CHO Cells
- Colforsin
- Cricetinae
- Cyclic AMP
- Dinoprostone
- GTP Phosphohydrolases
- GTP-Binding Proteins
- Molecular Sequence Data
- Mutation
- Precipitin Tests
- Receptors, Prostaglandin E