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Article

Early decline in the catecholamine release-inhibitory peptide catestatin in humans at genetic risk of hypertension.

Journal of hypertension - 1 Jul 2002

O'Connor Daniel T, Kailasam Mala T, Kennedy Brian P, Ziegler Michael G, Yanaihara Noboru, Parmer Robert J

Abstract excerpt

BACKGROUND: Hypertension is a complex trait with an ill-defined genetic predisposition, in which adrenergic mechanisms seem to be involved even at the early stages. Chromogranin A is a pro-hormone stored and released with catecholamines by exocytosis; its fragment catestatin, formed in vivo, inhibits further catecholamine release as an antagonist at the physiologic trigger for secretion, the neuronal nicotinic...

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Source

Identifiers

PMID: 12131530
DOI: 10.1097/00004872-200207000-00020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Early decline in the catecholamine release-inhibitory peptide catestatin in humans at genetic risk of hypertension.PMID 12131530Read ↗

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