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Article

Resequencing PNMT in European hypertensive and normotensive individuals: no common susceptibilily variants for hypertension and purifying selection on intron 1.

BMC medical genetics - 23 Jul 2007

Kepp Katrin, Juhanson Peeter, Kozich Viktor, Ots Mai, Viigimaa Margus, Laan Maris

Abstract excerpt

BACKGROUND: Human linkage and animal QTL studies have indicated the contribution of genes on Chr17 into blood pressure regulation. One candidate gene is PNMT, coding for phenylethanolamine-N-methyltransferase, catalyzing the synthesis of epinephrine from norepinephrine. METHODS: Fine-scale variation of PNMT was screened by resequencing hypertensive (n = 50) and normotensive (n = 50) individuals from two European...

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Identifiers

PMID: 17645789
DOI: 10.1186/1471-2350-8-47
PMCID: PMC1947951

Genes

PNMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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