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Article

Effects of chromogranin A deficiency and excess in vivo: biphasic blood pressure and catecholamine responses.

Journal of hypertension - 1 Apr 2010

Vaingankar Sucheta M, Li Ying, Biswas Nilima, Gayen Jiaur, Choksi Sonia, Rao Fangwen, Ziegler Michael G, Mahata Sushil K, O'Connor Daniel T

Abstract excerpt

OBJECTIVE: The phenotype of the chromogranin A (Chga) null (knockout) mouse is hypertensive. However, hypertensive humans and spontaneously hypertensive rats display elevated CHGA expression. This study addresses the paradox that both ablation and elevation of CHGA result in hypertension. METHODS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20139771
DOI: 10.1097/HJH.0b013e328336ed3e
PMCID: PMC2947860

Genes

CHGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20139771-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of chromogranin A deficiency and excess in vivo: biphasic blood pressure and catecholamine responses.PMID 20139771Read ↗

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