Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of p53 mutations on prognosis of patients with glioblastoma.

Cancer - 15 Jul 2002

Shiraishi Shoji, Tada Kenji, Nakamura Hideo, Makino Keishi, Kochi Masato, Saya Hideyuki, Kuratsu Jun-ichi, Ushio Yukitaka

Abstract excerpt

BACKGROUND: The influence of p53 mutations on the biology of astrocytic tumors is controversial. p53 is thought to be inactivated in the early stage of gliomagenesis; however, what role its inactivation plays in the malignancy of gliomas remains unknown. To understand the significance of p53 inactivation, the authors identified the locus of p53 gene mutation in glioma samples at different stages of progression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytoma
Share to Central Nervous System Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Genes, p53

Share to Glioblastoma

Share to Infant

Share to Prognosis

Share to Survival Rate

Source

Identifiers

PMID: 12124823
DOI: 10.1002/cncr.10677

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of p53 mutations on prognosis of patients with glioblastoma.PMID 12124823Read ↗

Roles of the functional loss of p53 and other genes in astrocytoma tumorigenesis and progression.Semantic proximity Read ↗

The p53 gene and its role in human brain tumors.Semantic proximity Read ↗

The p53 Pathway in GlioblastomaSemantic proximity Read ↗

Genetic alterations associated with glioma progression.Semantic proximity Read ↗

Reappraisal of p53 mutations in human malignant astrocytic neoplasms by p53 functional assay: comparison with conventional structural analyses.Semantic proximity Read ↗

TP53 and p53 statuses and their clinical impact in diffuse low grade gliomas.Semantic proximity Read ↗

Epidemiology and etiology of gliomas.Semantic proximity Read ↗

Absence of mutation of the p73 gene in astrocytic neoplasms.Semantic proximity Read ↗

Rare occurrence of inactivating p53 gene mutations in primary non-astrocytic tumors of the central nervous system: reappraisal by yeast functional assay.Semantic proximity Read ↗

Timing of p53 mutations during astrocytoma tumorigenesis.Semantic proximity Read ↗

Functional evaluation of p53 and PTEN gene mutations in gliomas.Semantic proximity Read ↗

Pattern of mutant p53 expression in human astrocytomas suggests the existence of alternate pathways of tumorigenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.