Article
Long-term potentiation and adenosine sensitivity are unchanged in the AS/AGU protein kinase Cgamma-deficient rat.
Neuroscience letters - 26 Jul 2002
Shahraki Ali, Stone Trevor W
Abstract excerpt
The AS/AGU rat is a spontaneously occurring mutation which exhibits locomotor abnormalities, reduced tyrosine hydroxylase levels in substantia nigra and lower extracellular levels of dopamine, making it a valuable model for some human locomotor disorders, and spontaneous chronic degeneration. The molecular defect is an absence of protein kinase Cgamma (PKCgamma), an enzyme suggested to play a role in synaptic...
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