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Article

The cAMP-protein kinase A signal transduction pathway modulates ethanol consumption and sedative effects of ethanol.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jul 2001

Wand G, Levine M, Zweifel L, Schwindinger W, Abel T

Abstract excerpt

Ethanol and other drugs of abuse modulate cAMP-PKA signaling within the mesolimbic reward pathway. To understand the role of the cAMP-PKA signal transduction in mediating the effects of ethanol, we have studied ethanol consumption and the sedative effects of ethanol in three lines of genetically modified mice. We report that mice with the targeted disruption of one Gsalpha allele as well as mice with reduced...

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Identifiers

PMID: 11438605
PMCID: PMC6762861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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