Article
Different phosphatase-dependent mechanisms mediate long-term depression and depotentiation of long-term potentiation in mouse hippocampal CA1 area.
The European journal of neuroscience - 1 Sept 2003
Jouvenceau Anne, Billard Jean-Marie, Haditsch Ursula, Mansuy Isabelle M, Dutar Patrick
Abstract excerpt
Two types of synaptic depression have been described in the hippocampus, long-term depression and depotentiation of long-term potentiation known to recruit the serine/threonine protein phosphatases PP1, PP2A and PP2B (calcineurin). The contribution of each of these protein phosphatases is controversial. To examine the role of the Ca2+/calmodulin-dependent protein phosphatase calcineurin in long-term depression...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
