Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of alpha-synuclein in synaptic glutamate release.

Neurobiology of disease - 1 Oct 2007

Gureviciene Irina, Gurevicius Kestutis, Tanila Heikki

Abstract excerpt

Defective mobilization of dopamine from the reserve pool has been reported in both alpha-synuclein knockout mice (KO) and pPrp-A30P transgenic mice. The present study extends these findings to glutamate release. Standard hippocampal slices were prepared from KO, pPrp-A30P, and C57BL/6J wild type (WT1) mice, as well as from mice with transgenic overexpression of wild type human alpha-synuclein (pSyn-hASY) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Synuclein
Share to Excitatory Postsynaptic Potentials
Share to Glutamic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neuronal Plasticity

Share to Organ Culture Techniques

Share to Patch-Clamp Techniques

Share to Synapses

Share to Synaptic Transmission

Source

Identifiers

PMID: 17689254
DOI: 10.1016/j.nbd.2007.06.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of alpha-synuclein in synaptic glutamate release.PMID 17689254Read ↗

Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice.Semantic proximity Read ↗

Alterations in corticostriatal synaptic plasticity in mice overexpressing human alpha-synuclein.Semantic proximity Read ↗

Aging and alpha-synuclein affect synaptic plasticity in the dentate gyrus.Semantic proximity Read ↗

Abnormal compartmentalization of norepinephrine in mouse dentate gyrus in alpha-synuclein knockout and A30P transgenic mice.Semantic proximity Read ↗

Glutamatergic synaptic resilience to overexpressed human alpha-synucleinSemantic proximity Read ↗

Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein.Semantic proximity Read ↗

Regulation of GABA(A) and glutamate receptor expression, synaptic facilitation and long-term potentiation in the hippocampus of prion mutant mice.Semantic proximity Read ↗

Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in miceSemantic proximity Read ↗

Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein.Semantic proximity Read ↗

Acute increase of α-synuclein inhibits synaptic vesicle recycling evoked during intense stimulation.Semantic proximity Read ↗

Age-related synaptic dysfunction in Tg2576 mice starts as a failure in early long-term potentiation which develops into a full abolishment of late long-term potentiation.Semantic proximity Read ↗

Chronic treatment with a MEK inhibitor reverses enhanced excitatory field potentials in Syngap1+/- mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.