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Article

Methamphetamine-induced hyperactivity and behavioral sensitization in PACAP deficient mice.

Peptides - 1 Sept 2007

Fujii Harumi, Ishihama Toshihiro, Ago Yukio, Shintani Norihito, Kakuda Michiya, Hashimoto Hitoshi, Baba Akemichi, Matsuda Toshio

Abstract excerpt

Mice lacking the PACAP gene (PACAP(-/-)) display psychomotor abnormalities such as novelty-induced hyperactivity and jumping behavior, and they show different responses to amphetamine, a typical psychostimulant. The present study examined the possible role of endogenous PACAP in methamphetamine (...

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Source

Identifiers

PMID: 17658665
DOI: 10.1016/j.peptides.2007.06.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17658665-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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