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Article

A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning.

Cell - 29 Dec 1995

Huang Y Y, Kandel E R, Varshavsky L, Brandon E P, Qi M, Idzerda R L, McKnight G S, Bourtchouladze R

Abstract excerpt

Using a genetic approach, we assessed the effects of mutations in protein kinase A (PKA) on long-term potentiation (LTP) in the mossy fiber pathway and its relationship to spatial and contextual learning. Ablation by gene targeting of the C beta 1 or the RI beta isoform of PKA produces a selectiv...

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PMID: 8548807
DOI: 10.1016/0092-8674(95)90146-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8548807-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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