Article
Impaired cerebellar long-term potentiation in type I adenylyl cyclase mutant mice.
Neuron - 1 Jun 1998
Storm D R, Hansel C, Hacker B, Parent A, Linden D J
Abstract excerpt
Activation of adenylyl cyclase and the consequent production of cAMP is a process that has been shown to be central to invertebrate model systems of information storage. In the vertebrate brain, it has been suggested that a presynaptic cascade involving Ca influx, cAMP production, and subsequent...
Topics
- Adenylyl Cyclases
- Animals
- Cell Membrane
- Cells, Cultured
- Cyclic AMP
- Electrophysiology
- Enzyme Inhibitors
- Excitatory Postsynaptic Potentials
- Gait
- Glutamic Acid
- Long-Term Potentiation
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mutation
- Nerve Fibers
- Psychomotor Performance
- Purkinje Cells