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Article

An interaction between the IL-4Ralpha gene and infection is associated with atopic eczema in young children.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jul 2002

Callard R E, Hamvas R, Chatterton C, Blanco C, Pembrey M, Jones R, Sherriff A, Henderson J

Abstract excerpt

BACKGROUND: A gain of function mutation (Q551- > R) in the IL-4 receptor alpha-chain (IL-4Ralpha) has been found to be associated with atopy in some studies but not others. The different results may be explained by interactions between the IL-4Ralpha polymorphism and environmental factors. OBJECTIVES: To identify interactions between the R551 mutation and environmental factors that are associated with atopy....

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Source

Identifiers

PMID: 12100043
DOI: 10.1046/j.1365-2222.2002.01414.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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