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Article

Interaction between variants in the interleukin-4 receptor alpha and interleukin-9 receptor genes in childhood wheezing: evidence from a birth cohort study.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Nov 2006

Melén E, Umerkajeff S, Nyberg F, Zucchelli M, Lindstedt A, Gullstén H, Wickman M, Pershagen G, Kere J

Abstract excerpt

BACKGROUND: Several polymorphisms in the IL-4 receptor alpha (IL4RA) gene have been associated with asthma and atopy, but with variable success in different populations. Immunologic studies suggest that IL4RA may interact with other cytokines and receptors, and gene-gene interactions have also been observed with respect to asthma. Such interactions have been proposed to explain partly the difficulties in...

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PMID: 17083349
DOI: 10.1111/j.1365-2222.2006.02577.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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