Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-10 promoter and IL4-Ralpha gene SNPs are associated with immediate beta-lactam allergy in atopic women.

Allergy - 1 Aug 2006

Guglielmi L, Fontaine C, Gougat C, Avinens O, Eliaou J-F, Guglielmi P, Demoly P

Abstract excerpt

BACKGROUND: Allergic reactions to beta-lactam antibiotics represent the most frequent cause of immunological drug reactions. OBJECTIVE: This study evaluates the involvement of genetic susceptibility factors in patients with immediate allergic reactions to beta-lactams. We examined 15 single nucleotide polymorphisms (SNP) of genes coding proteins implicated in immunoglobulin (Ig)E synthesis regulation. METHODS: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Hypersensitivity
Share to Antibody Formation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to beta-Lactams

Share to Case-Control Studies

Share to DNA Mutational Analysis

Share to Immunoglobulin E

Share to Interleukin-10

Share to Interleukin-4 Receptor alpha Subunit

Source

Identifiers

PMID: 16867043
DOI: 10.1111/j.1398-9995.2006.01067.x

Genes

STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-10 promoter and IL4-Ralpha gene SNPs are associated with immediate beta-lactam allergy in atopic women.PMID 16867043Read ↗

Gene–gene interactions of IL13 and IL4RA variants in immediate allergic reactions to betalactam antibioticsSemantic proximity Read ↗

Beta-lactam-induced immediate hypersensitivity reactions: A genome-wide association study of a deeply phenotyped cohort.Semantic proximity Read ↗

Polymorphisms and haplotype analysis of IL-4Ralpha Q576R and I75V in patients with penicillin allergy.Semantic proximity Read ↗

Genetic predisposition to parthenium dermatitis in an Indian cohort due to lower-producing genotypes of interleukin-10 (-) 1082 G>A and (-) 819 C>T loci but no association with interferon-γ (+) 874 A>T locus.Semantic proximity Read ↗

Biological and genetic determinants of atopy are predictors of immediate-type allergy to betalactams, in Spain.Semantic proximity Read ↗

Interleukin 10 receptor alpha subunit (IL-10RA) gene polymorphism and IL-10 serum levels in Egyptian atopic patients.Semantic proximity Read ↗

Genetic regulation of cervical antiinflammatory cytokine concentrations during pregnancy.Semantic proximity Read ↗

Associations of the IL2Ralpha, IL4Ralpha, IL10Ralpha, and IFN (gamma) R1 cytokine receptor genes with AIDS progression in a French AIDS cohort.Semantic proximity Read ↗

Interleukin-10 polymorphisms in Spanish IgA deficiency patients: a case-control and family study.Semantic proximity Read ↗

Interleukin-4RA gene polymorphism is associated with oral mucous membrane pemphigoid.Semantic proximity Read ↗

The alpha-chain of high-affinity receptor for IgE (FcepsilonRIalpha) gene polymorphisms and serum IgE levels.Semantic proximity Read ↗

Relationships between specific serum IgE, cytokines and polymorphisms in the IL‐4, IL‐4R<i>α</i> in patients with penicillins allergySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.