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Article

Polymorphisms of the IL-4, TNF-alpha, and Fcepsilon RIbeta genes and the risk of allergic disorders in at-risk infants.

American journal of respiratory and critical care medicine - 1 May 2000

Zhu S, Chan-Yeung M, Becker A B, Dimich-Ward H, Ferguson A C, Manfreda J, Watson W T, Paré P D, Sandford A J

Abstract excerpt

Polymorphisms in the TNF-alpha (A-308G), IL-4 (C-589T), and Fcalpha RIbeta (E237G) genes have been associated with asthma and related phenotypes. To determine the predictive value of these polymorphisms we have assessed their relative risk (RR) for the development of atopy, asthma, and rhinitis in a high-risk infant population that is being followed longitudinally from birth. DNA was extracted and genotyped for...

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PMID: 10806171
DOI: 10.1164/ajrccm.161.5.9906086

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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