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Article

MUC5AC and inflammatory mediators associated with respiratory outcomes in the British 1946 birth cohort.

Respirology (Carlton, Vic.) - 1 Aug 2013

Johnson Lauren, Shah Imran, Loh Andrew X, Vinall Lynne E, Teixeira Ana S, Rousseau Karine, Holloway John W, Hardy Rebecca, Swallow Dallas M

Abstract excerpt

BACKGROUND AND OBJECTIVE: Dysregulation of respiratory mucins, MUC5AC in particular, has been implicated in respiratory disease and MUC5AC expression is up-regulated in response to environmental challenges and inflammatory mediators. The aim of this study was to examine the effect of genetic variation on susceptibility to common respiratory conditions. METHODS: The association of MUC5AC and the closely linked...

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Source

Open in PubMed Open full text

Identifiers

PMID: 23551418
DOI: 10.1111/resp.12092
PMCID: PMC3784974

Genes

MUC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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