Article
The role of R576Q polymorphism of interleukin-4 receptor alpha gene in atopy: results of a family-based study design.
Journal of investigational allergology & clinical immunology - 1 Jan 2001
Rogala B, Rymarczyk B, Moczulski D, Grzeszczak W
Abstract excerpt
INTRODUCTION: There is strong evidence that the R576 allele of interleukin-4 receptor alpha gene (IL-4R) might predispose to atopy. To test this hypothesis, we examined the association between the R576Q polymorphism and atopy in a Polish population using the family-based study design. MATERIALS AND METHODS: 44 atopic patients (age range from 11 to 34 years) with pollen and house dust mite allergy or/and mild...
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