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Article

Parental smoking impairs vaccine responses in children with atopic genotypes.

The Journal of allergy and clinical immunology - 1 Feb 2007

Baynam Gareth, Khoo Siew-Kim, Rowe Julie, Zhang Guicheng, Laing Ingrid, Hayden Catherine, Kusel Merci, DeKlerk Nick, Sly Peter, Goldblatt Jack, Holt Patrick, LeSouef Peter

Abstract excerpt

BACKGROUND: Gene-environment interactions play central roles in controlling postnatal maturation of immune function, but their effects on infant vaccine responses are unknown. Genetic variants associated with atopy and the environmental factor of exposure to parental smoking (PS) of tobacco independently alter immune responses. OBJECTIVE: We sought to investigate the hypothesis that genetic variants associated...

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Identifiers

PMID: 17291854
DOI: 10.1016/j.jaci.2006.09.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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