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Article

The R576 IL-4 receptor alpha allele correlates with asthma severity.

The Journal of allergy and clinical immunology - 1 Nov 1999

Rosa-Rosa L, Zimmermann N, Bernstein J A, Rothenberg M E, Khurana Hershey G K

Abstract excerpt

BACKGROUND: Atopic disorders, including asthma, are very prevalent, affecting up to 40% of populations, and their incidence is on the rise. Although environmental factors are important in the development of atopy, there is a strong genetic predisposition. Several genes and chromosomal regions have been linked to atopy and asthma, supporting the polygenic nature of these disorders. IL-4 and IL-13 are T(H)2...

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Source

Identifiers

PMID: 10550746
DOI: 10.1016/s0091-6749(99)70082-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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