Article
Binding sites of different geometries for the 16-3 phage repressor.
Proceedings of the National Academy of Sciences of the United States of America - 25 Jun 2002
Papp Peter P, Nagy Tibor, Ferenczi Szilamér, Elõ Peter, Csiszovszki Zsolt, Buzás Zsuzsanna, Patthy András, Orosz László
Abstract excerpt
Prokaryotic repressor-operator systems provide exemplars for the sequence-specific interactions between DNA and protein. The crucial atomic contacts of the two macromolecules are attained in a compact, geometrically defined structure of the DNA-protein complex. The pitch of the DNA interface seems an especially sensitive part of this architecture because changes in its length introduce new spacing and rotational...
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