Article
DNA trajectory in the Gal repressosome.
Genes & development - 1 Aug 2004
Semsey Szabolcs, Tolstorukov Michail Y, Virnik Konstantin, Zhurkin Victor B, Adhya Sankar
Abstract excerpt
The Gal repressosome is a higher-order nucleoprotein complex that represses transcription of the gal operon in Escherichia coli. During the repressosome assembly, a DNA loop is formed by the interaction of two GalR dimers, bound to two spatially separated operators, OE and OI, flanking the gal promoters. Structure-based genetic analysis indicated that GalR homodimers interact directly and form a V-shaped stacked...
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