A DNA curvature can substitute phage phi 29 regulatory protein p4 when acting as a transcriptional repressor.

doi:10.1002/j.1460-2075.1991.tb04907.x

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Article

A DNA curvature can substitute phage phi 29 regulatory protein p4 when acting as a transcriptional repressor.

The EMBO journal - 1 Nov 1991

Rojo F, Salas M

Abstract excerpt

Binding of phage phi 29 regulatory protein p4 to its target sequences produces a strong bend in the DNA that is important for activation of the late A3 promoter (PA3). Protein p4 binding site in PA3 overlaps with the divergently transcribed main early promoter. PA2b, which suggested that p4 could...

Topics

Bacteriophages
Base Sequence
Binding Sites
DNA Fingerprinting
DNA, Viral
Electrophoresis, Polyacrylamide Gel
Hydroxides
Hydroxyl Radical
Kinetics
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Promoter Regions, Genetic
Transcription, Genetic
Viral Proteins

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