Article
A DNA curvature can substitute phage phi 29 regulatory protein p4 when acting as a transcriptional repressor.
The EMBO journal - 1 Nov 1991
Rojo F, Salas M
Abstract excerpt
Binding of phage phi 29 regulatory protein p4 to its target sequences produces a strong bend in the DNA that is important for activation of the late A3 promoter (PA3). Protein p4 binding site in PA3 overlaps with the divergently transcribed main early promoter. PA2b, which suggested that p4 could also act as a repressor. We show that protein p4 both excludes Bacillus subtilis sigma A-RNA polymerase from PA2b and...
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