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Article

A multigenerational family with multiple sclerosis.

Brain : a journal of neurology - 1 Jul 2002

Dyment D A, Cader M Z, Willer C J, Risch N, Sadovnick A D, Ebers G C

Abstract excerpt

We report a family with 15 individuals affected with multiple sclerosis present in three and possibly four generations. The segregation of multiple sclerosis within this pedigree is consistent with an autosomal dominant mode of inheritance with reduced penetrance. The clinical characteristics of the affected individuals are indistinguishable from those seen in sporadic multiple sclerosis with respect to sex...

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Identifiers

PMID: 12076998
DOI: 10.1093/brain/awf158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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