Article
A genome-wide scan in forty large pedigrees with multiple sclerosis.
Journal of human genetics - 1 Jan 2007
Willer Cristen J, Dyment David A, Cherny Stacey, Ramagopalan Sreeram V, Herrera Blanca M, Morrison Katie M E, Sadovnick A Dessa, Risch Neil J, Ebers George C
Abstract excerpt
The epidemiology of multiple sclerosis suggests that a complex interaction of genes and environment contribute to susceptibility. To enrich for families with large genetic effects and to potentially reduce genetic heterogeneity, we screened a sample of 18,794 probands and identified forty familie...
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