Article
HLA-DRB1*15 association with multiple sclerosis is confirmed in a multigenerational Italian family.
Functional neurology - 1 Jan 2000
Mosca L, Mantero V, Penco S, La Mantia L, De Benedetti S, Marazzi M R, Spreafico C, Erminio C, Grassi L, Lando G, Zagaria M, Agostoni E, Protti A
Abstract excerpt
Environmental and genetic factors seem to play a pathogenetic role in multiple sclerosis (MS). The genetic component is partly suggested by familial aggregation of cases; however, MS families with affected subjects over different generations have rarely been described. The aim of this study was to report clinical and genetic features of a multigenerational MS family and to perform a review of the literature on...
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