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Article

A vulnerability locus to multiple sclerosis maps to 7p15 in a region syntenic to an EAE locus in the rat.

Genes and immunity - 1 Jan 2004

Coppin H, Ribouchon M-T, Fontaine B, Edan G, Clanet M, Roth M-P

Abstract excerpt

Multiple sclerosis (MS) is a chronic immune-mediated demyelinating disease of the central nervous system. Evidence from family studies indicates a strong genetic component. Despite many studies of candidate genes, only an association with the HLA-DRB1*1501-DQB1*0602 haplotype has been generally detected, and HLA linkage established by transmission disequilibrium testing. A genome-wide scan revealed suggestive...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14735153
DOI: 10.1038/sj.gene.6364038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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